Journal :   Research Journal of Pharmacy and Technology

Volume No. :   2

Issue No. :  3

Year :  2009

Pages :   582-584

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Simultaneous Spectrophotometric Methods for Estimation of Cefixime and Erdosteine in Synthetic Mixture



Address:   Nanda RK*, Gaikwad J and Prakash A
Pad. Dr. D.Y.Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune-411 018.
*Corresponding Author
DOI No:

ABSTRACT:
Two simple, rapid, accurate and economical methods have been developed for the estimation of Cefixime and Erdosteine in synthetic mixture. First method is based on solving the simultaneous equation for the two drugs and second method is based on multicomponent analysis. Cefixime has absorbance maxima at 289.0 nm and Erdosteine at 235.0 nm using methanol as solvent for both methods. The Beer Lambert range was observed in concentration range of 10-50 ?g/ml for both Cefixime and Erdosteine. The results of both methods have been statistically validated and found to be satisfactory. The recovery studies confirmed the accuracy of the proposed methods.
KEYWORDS:
Cefixime, Erdosteine, Simultaneous equation, Multicomponant.
Cite:
Nanda RK, Gaikwad J, Prakash A. Simultaneous Spectrophotometric Methods for Estimation of Cefixime and Erdosteine in Synthetic Mixture. Research J. Pharm. and Tech.2 (3): July-Sept. 2009,;Page 582-584.
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