Journal :   Research Journal of Pharmacy and Technology

Volume No. :   2

Issue No. :  3

Year :  2009

Pages :   572-577

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Design of Pop Rice Based ORS Formulation: Physicochemical and Microbiological Investigation



Address:   Rumana Jahangir1, Md. Ifte Khairul Alam2, Tasnuva Haque1*, Md. Mesbah Uddin Talukder3 and Shammy Sarwar1
1Depatment of Pharmacy, Stamford University Bangladesh, Dhaka-1217. Bangladesh
2Healthcare Pharmaceuticals Limited, 71-72 Old Elephant Road, Eskaton Garden, Dhaka-1000, Bangladesh.
3Derpartment of Pharmacy, The University of Asia Pacific, Dhaka-1209, Bangladesh.
*Corresponding Author
DOI No:

ABSTRACT:
Pop rice (Khoi) prepared from paddy (locally called Gios Paddy) without sand heating. Then it was grinded to fine powder and then packed into a sachet (high density polyethylene sachet). The salt ingredients were kept separately into the same sachet. After reconstitution all the physicochemical and microbiological tests were performed time to time to investigate whether formulation can be effectively used for the treatment of diarrhoea upto 8 hours. It was observed that the electrolytes concentration and osmolarity remained same in addition to small change of pH within this time peroid. Furthermore, total bacterial count and total fungal count were found within the standard specification upto 6 hours and also the pathogenic bacteria was found absent in the pop rice based ORS solution. Therefore, pop rice powder based ORS solution can be easily and effectively used for the treatment of diarrhoea.
KEYWORDS:
Pop rice, Oral Rhydration Salt, physicochemical and microbiological investigation.
Cite:
Rumana Jahangir, Ifte Khairul Alam, Tasnuva Haque, Mesbah Uddin Talukder, Shammy Sarwar. Design of Pop Rice Based ORS Formulation: Physicochemical and Microbiological Investigation. Research J. Pharm. and Tech.2 (3): July-Sept. 2009,;Page 572-577.
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