Journal :   Research Journal of Pharmacy and Technology

Volume No. :   2

Issue No. :  2

Year :  2009

Pages :   409-411

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Anti-Inflammatory Activity of Ethanolic and Acetone Extracts of Bauhnia Variegate



Address:   D SheshadriShekar* C Velmurugan, G Ramakrishnan and B Vivek
Department of Pharmacology, Sri K .V College of Pharmacy, M.G.Road, Chickballapur-562101.
*Corresponding Author
DOI No:

ABSTRACT:
The ethanolic and acetone extracts of Bauhnia variegate bark was examined for anti-inflammatory in experimental animals. In this study both acute and sub-acute inflammation models were used to evaluate the anti-inflammatory activity of the Bauhnia variegate. In acute model carrageenan was used to induce inflammation in rat hind paw and in sub-acute inflammation, cotton pellet induced granuloma was performed. The bark of ethanolic and acetone extracts of bauhnia variegate at the doses of 400 mg/kg shows significant (p<0.001) inhibition of inflammation against both acute and sub-acute anti-inflammatory model. The percentage inhibition of ethanolic and acetone extract of Bauhnia variegate both acute and sub-acute anti-inflammatory model was 35.29%, 43.14% and 33.53%, 42.20% respectively. According to our results both the extracts of Bauhnia variegate in doses of 400 mg/kg reveals anti-inflammatory activity and supports tribal claim.
KEYWORDS:
Anti-inflammatory, Carrageenan, Cotton pellet granuloma and Bauhnia variegate.
Cite:
D SheshadriShekar, C Velmurugan, G Ramakrishnan, B Vivek. Anti-Inflammatory Activity of Ethanolic and Acetone Extracts of Bauhnia Variegate. Research J. Pharm. and Tech.2(2): April.-June.2009,;Page 409-411.
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