Journal :   Research Journal of Pharmacy and Technology

Volume No. :   2

Issue No. :  1

Year :  2009

Pages :   186-190

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Preparation, Numerical Optimization and Evaluation of Ciprofloxacin PLGA and PLA Nanoparticles by Solvent Displacement Technique



Address:   S Rajarajan1* and R Chandramouli2
1Karnataka College of Pharmacy, Bangalore 560 064, Karnataka
2CARISM, Sastra University, Thanjavur - 613 402. Tamil Nadu, India.
*Corresponding Author
DOI No:

ABSTRACT:
The aim of the current study to prepare and characterization of drug as a nanoparticles by numerical optimization method by using ciprofloxacin as a model drug and using Ploy (Lactic –co- glycolic acid) PLGA and (Poly lactic acid) PLA. The particles were prepared by solvent displacement technique. The formulations were evaluated in terms of surface character, Particle size, drug loading efficacy and separation of free drug. The mean diameter was dependent on Polymer concentration.
KEYWORDS:
Nanoparticles; ciprofloxacin; Ploy (Lactic –co- glycolic acid) PLGA and (Poly lactic acid) PLA.
Cite:
S Rajarajan, R Chandramouli. Preparation, Numerical Optimization and Evaluation of Ciprofloxacin PLGA and PLA Nanoparticles by Solvent Displacement Technique. Research J. Pharm. and Tech. 2(1): Jan.-Mar. 2009; Page 186-190.
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