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Journal :   Research Journal of Pharmacy and Technology

Volume No. :   2

Issue No. :  1

Year :  2009

Pages :   128-130

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Anthelmintic Activity of Extracts of Trigonella Foenum-Graecum Linn

Address:   HA Sawarkar*, SS Khadabadi, NB Banarase BP Muley, PB Aswar
Government College of Pharmacy, Pharmacognosy and Phytochemistry Department, Amravati- 444 604(M.S.) India
*Corresponding Author

The crude extracts of Trigonella foenum-graecum Linn. (Leguminaceae) were evaluated for anthelmintic activity using adult earthworms; the seeds of Trigonella foenum-graecum were extracted with solvents namely pet. ether, chloroform, ethanol and hot water. The paralytic effects of all the extracts are compared with Piperazine Citrate (3%). With higher doses (50mg/mL) of pet ether and ethanol extracts, the effects were potent than that of 3% piperazine citrate. However, there was no final recovery in the case of worms treated with all four extracts in contrast to piperazine citrate with which the paralysis was reversible and the worms recovered completely within 5 h. The result shows that the pet ether and ethanol extracts possesses potent wormicidal activity and thus, may be useful as an anthelmintic.
Anthelmintic, Trigonella foenum-graecum, paralysis, piperazine citrate.
HA Sawarkar, SS Khadabadi, NB Banarase BP Muley, PB Aswar. Anthelmintic Activity of Extracts of Trigonella Foenum-Graecum Linn. Research J. Pharm. and Tech. 2(1): Jan.-Mar. 2009; Page 128-130.
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