Journal :   Research Journal of Pharmacy and Technology

Volume No. :   2

Issue No. :  1

Year :  2009

Pages :   114-116

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Hepatoprotective activity of Momordicia diocia Roxb fruits in Carbon tetrachloride induced hepatotoxic Rats



Address:   Prasannakumar BR * Mohammed Khallel and P Shankar
Department of Pharmacology, MMU College of Pharmacy, Ramanagaram-571511
*Corresponding Author
DOI No:

ABSTRACT:
The objective of this study was to evaluate the hepatoprotective activity of the fruits of Momordicia diocia by preparing different extracts and the resultant extract were screened for the hepatoprotective activity. The ethyl acetate and ethanolic extracts of Momordicia diocia fruits were prepared and subjected for phytochemical screening and tested for their hepatoprotective activity in carbon tetrachloride induced hepatotoxic rats. Phytochemical screening showed positive test for steroids, triterpenoids and glycosides (ethanolic extract). The ethyl acetate and ethanolic extracts have shown significant hepatoprotective activity at a dose of 200mg/kg.p.o. The study results suggested that Momordicia diocia fruits possess potential hepatoprotective activity.
KEYWORDS:
Momordicia diocia, Hepatoprotective activity, screening .
Cite:
Prasannakumar BR, Mohammed Khallel, P Shankar. Hepatoprotective activity of Momordicia diocia Roxb fruits in Carbon tetrachloride induced hepatotoxic Rats. Research J. Pharm. and Tech. 2(1): Jan.-Mar. 2009; Page 114-116.
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