Journal :   Research Journal of Pharmacy and Technology

Volume No. :   1

Issue No. :  4

Year :  2008

Pages :   430-432

ISSN Print :  0974-3618

ISSN Online :  0974-360X


Registration

Allready Registrered
Click to Login

Validated Spectroscopic Method for Estimation of Aceclofenac from Tablet Formulation



Address:   Rohit Shah*, Chandrakant Magdum, Shital Kumar Patil, Dhanya Kumar Chougule and Nilofar Naikwade
Appasaheb Birnale College of Pharmacy, Sangli South Shivajinagar, Sangli – 416416. Maharashtra
*Corresponding Author
DOI No:

ABSTRACT:
Aceclofenac is a non steroidal anti-inflammatory drug with good analgesic and anti-rheumatic properties. Various methods for analysis of the same are available but are time consuming and expensive. Here we have developed a new, precise and simple UV spectrophotometric method for estimation of aceclofenac from tablet formulation. The drug obeyed the Beer’s law and showed good correlation. It showed absorption maxima at 273 nm; in phosphate buffer pH 7.4. The linearity was observed between 0 – 20 mcg/mL. The results of analysis were validated by recovery studies. The recovery was more than 99%. The method was found to be simple, accurate, precise, economical and robust.
KEYWORDS:
Aceclofenac, UV–Vis Spectrophotometry, Recovery.
Cite:
Rohit Shah, Chandrakant Magdum, Shital Kumar Patil, Dhanya Kumar Chougule, Nilofar Naikwade. Validated Spectroscopic Method for Estimation of Aceclofenac from Tablet Formulation. Research J. Pharm. and Tech. 1(4): Oct.-Dec. 2008;Page 430-432.
[View HTML]      [View PDF]



Visitor's No. :   366544