Journal :   Research Journal of Pharmacy and Technology

Volume No. :   1

Issue No. :  4

Year :  2008

Pages :   370-373

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Characterization of Ocular Delivery of Reverse Micelles Bearing Insulin

Address:   SK Jain3, R Chandra2 and AK Rai1*
1Pranveer Singh Institute of Technology Bhauti, Kalpi Road, Kanpur India
2Institute of Pharmacy Bundelkhand University, Jhansi-284128 (U.P) India
3Department of Pharmaceutical Sciences, Dr. H.S.Gour University, Sagar-470003 (M.P) India
*Corresponding Author

Reverse micelle system bearing insulin was developed for controlled and prolonged release of drug through ocular route. The system was prepared by using cetyl tri-ammonium bromide and span-60 separately with organic solvent isopropyl myristate. The effect of temperature and polarity on the system was studied by measuring the drug content. In-vitro drug release study was carried out by using a Frang diffusion cell and artificial tear solution as diffusion medium. It was observed that the micellar systems exhibited prolonged and controlled release of insulin.
Reverse micelles, Insulin, Ocular delivery.
SK Jain, R Chandra, AK Rai. Characterization of Ocular Delivery of Reverse Micelles Bearing Insulin. Research J. Pharm. and Tech. 1(4): Oct.-Dec. 2008;Page 370-373.
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