Journal :   Research Journal of Pharmacy and Technology

Volume No. :   1

Issue No. :  4

Year :  2008

Pages :   370-373

ISSN Print :  0974-3618

ISSN Online :  0974-360X


Registration

Allready Registrered
Click to Login

Characterization of Ocular Delivery of Reverse Micelles Bearing Insulin



Address:   SK Jain3, R Chandra2 and AK Rai1*
1Pranveer Singh Institute of Technology Bhauti, Kalpi Road, Kanpur India
2Institute of Pharmacy Bundelkhand University, Jhansi-284128 (U.P) India
3Department of Pharmaceutical Sciences, Dr. H.S.Gour University, Sagar-470003 (M.P) India
*Corresponding Author
DOI No:

ABSTRACT:
Reverse micelle system bearing insulin was developed for controlled and prolonged release of drug through ocular route. The system was prepared by using cetyl tri-ammonium bromide and span-60 separately with organic solvent isopropyl myristate. The effect of temperature and polarity on the system was studied by measuring the drug content. In-vitro drug release study was carried out by using a Frang diffusion cell and artificial tear solution as diffusion medium. It was observed that the micellar systems exhibited prolonged and controlled release of insulin.
KEYWORDS:
Reverse micelles, Insulin, Ocular delivery.
Cite:
SK Jain, R Chandra, AK Rai. Characterization of Ocular Delivery of Reverse Micelles Bearing Insulin. Research J. Pharm. and Tech. 1(4): Oct.-Dec. 2008;Page 370-373.
[View HTML]      [View PDF]



Visitor's No. :   433406