Journal :   Research Journal of Pharmacy and Technology

Volume No. :   1

Issue No. :  3

Year :  2008

Pages :   290-291

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Evaluation of Diuretic Activity of Alternanthera Sessilis (L.)



Address:   S Prakash Rao1*, Sushil Bhargava1 and Surendra Saraf 2
1Department of Pharmacognosy, Columbia Institute of Pharmacy, Raipur 493111 (C.G.)
2Department of Biotechnology, Columbia Institute of Pharmacy, Raipur 493111 (C.G.)
* Corresponding Author
DOI No:

ABSTRACT:
The plant Alternanthera sessilis (L.) R. Br. Ex DC belonging to the family Amaranthaceae was selected for the project, on the basis of ethnobotanical information, and easy availability. The diuretic activity of hydro-ethanolic extract was evaluated by lipschitz et.al method. The parameters taken for each individual rat were body weight total urine volume urine concentrations of Na+, Cl-, Na+ and K+ concentration were measured by flame photometry and Cl- concentrations was estimated titrimetrically. Frusemide was used as reference drug while normal saline solution was used as control. Hydroalcoholic extracts caused marked increase in Na+ Cl-, and decrease K+ level in urine.
KEYWORDS:
Diuretic, Hydroalcoholic, Urine.
Cite:
S Prakash Rao, Sushil Bhargava, Surendra Saraf . Evaluation of Diuretic Activity of Alternanthera Sessilis (L.). Research J. Pharm. and Tech. 1(3): July-Sept. 2008; Page 290-291.
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