Journal :   Research Journal of Pharmacy and Technology

Volume No. :   1

Issue No. :  3

Year :  2008

Pages :   276-277

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Spectrophotometric Estimation of Omeprazole in Pharmaceutical Dosage Form



Address:   Rakesh Singh and Swarnlata Saraf*
Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur 492 010 (CG) India
* Corresponding Author
DOI No:

ABSTRACT:
Zollinger Ellison syndrome, chronic peptic ulcer, and GERD are the disease condition which require to administered drug for a long period. Omeprazole belongs to the class of proton pump inhibitors widely used for such disease conditions. A simple, accurate, rapid, sensitive and economical spectrophotometric method for the determination of omeprazole in its pharmaceutical dosage forms has been developed. Omeprazole shows absorption maxima at 298.4 nm and obeyed Lambert Beer’s law in the concentration range of 2-18µ g/ml in the 6.8 phosphate buffer. The accuracy and reproducibility of the proposed method was statistically validated by recovery studies
KEYWORDS:
Omeprazole, spectrophotometric method, Proton pump inhibitor.
Cite:
Rakesh Singh, Swarnlata Saraf. Spectrophotometric Estimation of Omeprazole in Pharmaceutical Dosage Form. Research J. Pharm. and Tech. 1(3): July-Sept. 2008; Page 276-277.
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