Journal :   Research Journal of Pharmacy and Technology

Volume No. :   1

Issue No. :  3

Year :  2008

Pages :   204-206

ISSN Print :  0974-3618

ISSN Online :  0974-360X


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Effect of Mucuna pruriens Seed Extracts on Drug Induced Myelosuppression test using albino rats



Address:   S. Nayak1* and VK Dixit2
1Bansal College of Pharmacy, Kokta, Anandnagar, Bhopal. 462021
2Department of Pharmaceutical Sciences, Dr. Hari Singh Gour University, Sagar. 470003
DOI No:

ABSTRACT:
Seeds of Mucuna pruriens were tested for drug induced myelosuppression test using cyclophosphamide as cytotoxic drug. Ethanolic extract (50, 100 and 200mg/kg body weight, orally) its chloroform soluble fraction and insoluble fraction (50, 80 and 100 mg/kg body weight, orally) were studied on albino rats. Results of present finding suggests the ethanolic extract and its both chloroform soluble and insoluble fractions significantly (p<0.05) protect the effect of cyclophosphamide as observed by hematological studies. These investigations justifies the diversified use of Mucuna pruriens in the traditional system of medicine.
KEYWORDS:
Mucuna pruriens, Myelosuppression, Cyclophosphamide.
Cite:
S. Nayak, VK Dixit. Effect of Mucuna pruriens Seed Extracts on Drug Induced Myelosuppression test using albino rats. Research J. Pharm. and Tech. 1(3): July-Sept. 2008; Page 204-206.
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